Founded in 1974 by pharmacists Conrad Hoegstedt and Ed Mansfield at Pharmaceutical Specialties, Inc. (PSI), Vanicream was created specifically for patients with sensitive skin. The brand is a gold standard in dermatology, known for its “free of” philosophy—omitting common chemical irritants like dyes, fragrance, masking fragrance, lanolin, parabens, and formaldehyde. Their medical-grade formulas are designed to be non-comedogenic and hypoallergenic, making them a staple for individuals with eczema, psoriasis, and highly reactive skin.